Gene/Protein Search
Synaptic-protein-tree
Browse Proteins
Compound Search
Browse Compounds
Chorea Huntington
Epilepsy
Multiple Sclerosis
Parkinson Disease
Schizophrenia
Interactive Network
Synapse specific Pathways
KEGG Pathways
Experimental Data (private)
FAQ
Contact
Links
ProTox 3.0 Model Descriptions
Please select a model :
------Select a model------
Oral toxicity
Hepatotoxicity
Neurotoxicity
Cardiotoxicity
Nephrotoxicity
Respiratory toxicity
Carcinogenicity
Immunotoxicity
Mutagenicity
Cytotoxicity
BBB-barrier
Ecotoxicity
Clinical toxicity
Nutritional toxicity
----------------Toxicological Pathways----------------
Aryl hydrocarbon Receptor (AhR)
Androgen Receptor (AR)
Androgen Receptor Ligand Binding Domain (AR-LBD)
Aromatase
Estrogen Receptor Alpha (ER)
Estrogen Receptor Ligand Binding Domain (ER-LBD)
Peroxisome Proliferator Activated Receptor Gamma (PPAR-Gamma)
Nuclear factor (erythroid-derived 2)-like 2/antioxidant responsive element (nrf2/ARE)
Heat shock factor response element (HSE)
Mitochondrial membrane potential (MMP)
Phosphoprotein (Tumor Supressor) p53
ATPase family AAA domain-containing protein 5 (ATAD5)
Thyroid hormone receptor alpha (THRα)
Thyroid hormone receptor beta (THRβ)
Transtyretrin (TTR)
Ryanodine receptor (RYR)
GABA receptor (GABAR)
Glutamate N-methyl-D-aspartate receptor (NMDAR)
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor (AMPAR)
Kainate receptor (KAR)
Achetylcholinesterase (AChE)
Constitutive androstane receptor (CAR)
Pregnane X receptor (PXR)
NADH-quinone oxidoreductase (NADHOX)
Voltage gated sodium channel (VGSC)
Na+/I- symporter (NIS)
Cytochrome CYP1A2
Cytochrome CYP2C19
Cytochrome CYP2C9
Cytochrome CYP2D6
Cytochrome CYP3A4
Cytochrome CYP2E1
Toxicity Targets
